Gene : HAT A T. thermophila SB210

DB identifier  ? TTHERM_00248390 Secondary Identifier  ? | PreTt02535 | 21.m00382 | GCN5
M 02  19.6133 M 1012  -4.33688
M 1214  -7.03591 M 1416  1.77426
M 1618  -6.48702 M 24  -3.28875
M 46  23.1101 M 68  -3.92589
M 810  -16.0 Signalp  N
Signalp _ D  0.106 Tmhmm  {'length':'418','tmhs':'0','segments':[['outside','1','418']]}

Sequence Feature Displayer

Disease Displayer

Signalp Displayer

Tmhmm Displayer

1 Organism

Name Taxon Id
Tetrahymena thermophila SB210 312017

1 Proteins


Organism . Name
Length
Tetrahymena thermophila SB210 473  

1 Synonyms

Value
TTHERM_00248390

Genomics

Gene Ontology Displayer

Gene Structure Displayer

J Browse Displayer

Proteins

1 Proteins


Organism . Name
Length
Tetrahymena thermophila SB210 473  
 

Other

2 Data Sets

Name URL
Tetrahymena thermophila genome  
GO Annotation from TGD  

19 Publications

First Author Title Year Journal Volume Pages PubMed ID
Sobel RE Non-random acetylation of histone H4 by a cytoplasmic histone acetyltransferase as determined by novel methodology. 1994 J Biol Chem 269 18576-82 8034606
Morris SA Identification of histone H3 lysine 36 acetylation as a highly conserved histone modification. 2007 J Biol Chem 282 7632-40 17189264
Ohba R A novel H2A/H4 nucleosomal histone acetyltransferase in Tetrahymena thermophila. 1999 Mol Cell Biol 19 2061-8 10022893
Trievel RC Application of a fluorescent histone acetyltransferase assay to probe the substrate specificity of the human p300/CBP-associated factor. 2000 Anal Biochem 287 319-28 11112280
Zheng Y Fluorescence analysis of a dynamic loop in the PCAF/GCN5 histone acetyltransferase. 2005 Biochemistry 44 10501-9 16060659
Lin Y Solution structure of the catalytic domain of GCN5 histone acetyltransferase bound to coenzyme A. 1999 Nature 400 86-9 10403255
Rojas JR Structure of Tetrahymena GCN5 bound to coenzyme A and a histone H3 peptide. 1999 Nature 401 93-8 10485713
Kuo MH Transcription-linked acetylation by Gcn5p of histones H3 and H4 at specific lysines. 1996 Nature 383 269-72 8805705
Roth SY The subunit-exchange model of histone acetylation. 1996 Trends Cell Biol 6 371-5 15157517
Utley RT Transcriptional activators direct histone acetyltransferase complexes to nucleosomes. 1998 Nature 394 498-502 9697775
Clements A Structural basis for histone and phosphohistone binding by the GCN5 histone acetyltransferase. 2003 Mol Cell 12 461-73 14536085
Brownell JE An activity gel assay detects a single, catalytically active histone acetyltransferase subunit in Tetrahymena macronuclei. 1995 Proc Natl Acad Sci U S A 92 6364-8 7603997
Poux AN Molecular basis for Gcn5/PCAF histone acetyltransferase selectivity for histone and nonhistone substrates. 2003 Biochemistry 42 14366-74 14661947
Couture JF Histone-modifying enzymes: encrypting an enigmatic epigenetic code. 2006 Curr Opin Struct Biol 16 753-60 17070031
Brownell JE Tetrahymena histone acetyltransferase A: a homolog to yeast Gcn5p linking histone acetylation to gene activation. 1996 Cell 84 843-51 8601308
Tan S One HAT size fits all? 2001 Nat Struct Biol 8 8-10 11135657
Langer MR Modulating acetyl-CoA binding in the GCN5 family of histone acetyltransferases. 2002 J Biol Chem 277 27337-44 11994311
Tsukiyama T Chromatin remodeling and transcription. 1997 Curr Opin Genet Dev 7 182-91 9115421
Hettmann C Cloning and analysis of a Toxoplasma gondii histone acetyltransferase: a novel chromatin remodelling factor in Apicomplexan parasites. 1999 Nucleic Acids Res 27 4344-52 10536141