Gene : PDD1 T. thermophila SB210

DB identifier  ? TTHERM_00125280 Secondary Identifier  ? | PreTt09290 | 9.m00311 | 3699.m00021
M 02  126.207 M 1012  -21.913
M 1214  5.95614 M 1416  -11.0742
M 1618  31.1371 M 24  55.2452
M 46  -18.737 M 68  17.0593
M 810  -51.2969 Signalp  N
Signalp _ D  0.103 Tmhmm  {'length':'525','tmhs':'0','segments':[['outside','1','525']]}

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1 Organism

Name Taxon Id
Tetrahymena thermophila SB210 312017

1 Proteins


Organism . Name
Length
Tetrahymena thermophila SB210 477  

1 Synonyms

Value
TTHERM_00125280

Genomics

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Proteins

1 Proteins


Organism . Name
Length
Tetrahymena thermophila SB210 477  
 

Other

2 Data Sets

Name URL
Tetrahymena thermophila genome  
GO Annotation from TGD  

20 Publications

First Author Title Year Journal Volume Pages PubMed ID
Nikiforov MA A novel chromodomain protein, pdd3p, associates with internal eliminated sequences during macronuclear development in Tetrahymena thermophila. 2000 Mol Cell Biol 20 4128-34 10805754
Smothers JF Pdd1p associates with germline-restricted chromatin and a second novel anlagen-enriched protein in developmentally programmed DNA elimination structures. 1997 Development 124 4537-45 9409671
Liu Y RNAi-dependent H3K27 methylation is required for heterochromatin formation and DNA elimination in Tetrahymena. 2007 Genes Dev 21 1530-45 17575054
Duharcourt S Role of histone deacetylation in developmentally programmed DNA rearrangements in Tetrahymena thermophila. 2002 Eukaryot Cell 1 293-303 12455963
Liu Y Histone H3 lysine 9 methylation is required for DNA elimination in developing macronuclei in Tetrahymena. 2004 Proc Natl Acad Sci U S A 101 1679-84 14755052
Taverna SD Methylation of histone h3 at lysine 9 targets programmed DNA elimination in tetrahymena. 2002 Cell 110 701-11 12297044
Jenuwein T Molecular biology. An RNA-guided pathway for the epigenome. 2002 Science 297 2215-8 12351775
Fillingham JS Molecular genetic analysis of an SNF2/brahma-related gene in Tetrahymena thermophila suggests roles in growth and nuclear development. 2006 Eukaryot Cell 5 1347-59 16896218
Madireddi MT Identification of a novel polypeptide involved in the formation of DNA-containing vesicles during macronuclear development in Tetrahymena. 1994 Dev Biol 165 418-31 7958410
Cheng CY A domesticated piggyBac transposase plays key roles in heterochromatin dynamics and DNA cleavage during programmed DNA deletion in Tetrahymena thermophila. 2010 Mol Biol Cell 21 1753-62 20357003
Maercker C A nuclear protein involved in apoptotic-like DNA degradation in Stylonychia: implications for similar mechanisms in differentiating and starved cells. 1999 Mol Biol Cell 10 3003-14 10473642
Coyne RS Parental expression of the chromodomain protein Pdd1p is required for completion of programmed DNA elimination and nuclear differentiation. 1999 Mol Cell 4 865-72 10619033
Yao MC Identification of novel chromatin-associated proteins involved in programmed genome rearrangements in Tetrahymena. 2007 J Cell Sci 120 1978-89 17519286
Callebaut I Hydrophobic cluster analysis reveals a third chromodomain in the Tetrahymena Pdd1p protein of the chromo superfamily. 1997 Biochem Biophys Res Commun 235 103-7 9196044
Smothers JF Programmed DNA degradation and nucleolar biogenesis occur in distinct organelles during macronuclear development in Tetrahymena. 1997 J Eukaryot Microbiol 44 79-88 9109258
Janetopoulos C The conjusome: a novel structure in Tetrahymena found only during sexual reorganization. 1999 J Cell Sci 112 ( Pt 7) 1003-11 10198282
Rexer CH Lia1p, a novel protein required during nuclear differentiation for genome-wide DNA rearrangements in Tetrahymena thermophila. 2007 Eukaryot Cell 6 1320-9 17586719
Madireddi MT Pdd1p, a novel chromodomain-containing protein, links heterochromatin assembly and DNA elimination in Tetrahymena. 1996 Cell 87 75-84 8858150
Schwope RM Mutations in Pdd1 reveal distinct requirements for its chromodomain and chromoshadow domain in directing histone methylation and heterochromatin elimination. 2014 Eukaryot Cell 13 190-201 24297443
Mochizuki K Analysis of a piwi-related gene implicates small RNAs in genome rearrangement in tetrahymena. 2002 Cell 110 689-99 12297043