Gene : TIF1 T. thermophila SB210

DB identifier  ? TTHERM_00048810 Secondary Identifier  ? | PreTt11261 | 3.m01664 | ssA-TIBF | 3824.m03019
M 02  1.96096 M 1012  0.306223
M 1214  -0.813508 M 1416  -0.298966
M 1618  0.0899037 M 24  -1.89998
M 46  -0.393707 M 68  0.210475
M 810  1.49187 Signalp  N
Signalp _ D  0.108 Tmhmm  {'length':'212','tmhs':'0','segments':[['outside','1','212']]}

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1 Organism

Name Taxon Id
Tetrahymena thermophila SB210 312017

1 Proteins

Organism . Name
Tetrahymena thermophila SB210 163  

1 Synonyms



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1 Proteins

Organism . Name
Tetrahymena thermophila SB210 163  


2 Data Sets

Name URL
Tetrahymena thermophila genome  
GO Annotation from TGD  

10 Publications

First Author Title Year Journal Volume Pages PubMed ID
Mohammad M Characterization of a novel origin recognition complex-like complex: implications for DNA recognition, cell cycle control, and locus-specific gene amplification. 2003 Mol Cell Biol 23 5005-17 12832485
Hou Z A single-stranded DNA binding protein that specifically recognizes cis-acting sequences in the replication origin and transcriptional promoter region of Tetrahymena rDNA. 1995 Biochemistry 34 4583-92 7718560
Morrison TL TIF1 Represses rDNA replication initiation, but promotes normal S phase progression and chromosome transmission in Tetrahymena. 2005 Mol Biol Cell 16 2624-35 15772155
Saha S Cloning and biochemical analysis of the tetrahymena origin binding protein TIF1: competitive DNA binding in vitro and in vivo to critical rDNA replication determinants. 2001 J Biol Chem 276 45417-26 11577092
Mohammad MM Tetrahymena ORC contains a ribosomal RNA fragment that participates in rDNA origin recognition. 2007 EMBO J 26 5048-60 18007594
Yue M Conserved cis- and trans-acting determinants for replication initiation and regulation of replication fork movement in tetrahymenid species. 1998 Nucleic Acids Res 26 4635-44 9753731
Saha S Allele-specific protein-DNA interactions between the single-stranded DNA-binding protein, ssA-TIBF, and DNA replication determinants in Tetrahymena. 2000 J Mol Biol 295 423-39 10623536
Yakisich JS TIF1 activates the intra-S-phase checkpoint response in the diploid micronucleus and amitotic polyploid macronucleus of Tetrahymena. 2006 Mol Biol Cell 17 5185-97 17005912
Mohammad M Three different proteins recognize a multifunctional determinant that controls replication initiation, fork arrest and transcription in Tetrahymena. 2000 Nucleic Acids Res 28 843-51 10637338
Umthun AR Identification of DNA-binding proteins that recognize a conserved type I repeat sequence in the replication origin region of Tetrahymena rDNA. 1994 Nucleic Acids Res 22 4432-40 7971273